Oddsmakers see the Buckeyes a near lock even in the Big Ten Conference odds, where they sit at -230. Ohio State is a team that is aiming higher than just a conference championship. Wisconsin vs Ohio State Opening Spread/Odds/Line Let’s take a look at the opening Wisconsin vs Ohio State odds and analyze which direction the line is likely to move. Wisconsin just piled up 66 points against New Mexico State on Saturday. After that, easy wins over Arkansas State and Toledo have them ready for Wisconsin. Ohio State started slowly against Notre Dame but won by 11. As hard as this will be for Wisconsin fans to here, this is a game that may be as one-sided as the point spread suggests. 3 Ohio State is listed as a 17-point favorite at home versus Wisconsin as the two rivals prepare for their first meeting in three years. Read below for the full Wisconsin vs Ohio State opening odds and line movement prediction.The Buckeyes are aiming for a 4-0 start, while the Badgers would move to 3-1 if they pull off the upset.3 Ohio State has opened as a 17-point favorite against Wisconsin on Sept 24 Mandatory Credit: Joseph Maiorana-USA TODAY Sports (18) catches the touchdown during the second quarter against the Toledo Rockets at Ohio Stadium. Columbus, Ohio, USA Ohio State Buckeyes wide receiver Marvin Harrison Jr.